Radiation therapy can accelerate atherosclerotic changes. Macrophages and monocytes play an important role in atherosclerosis and plaque behaviors. Inflammation within these plaques can be quantitatively assessed by measuring T2* value of these plaques following intravenous administration of super paramagnetic iron oxide nanoparticles. From the cohort of pancreatic cancer patient who underwent MRI scans before and after administration of super paramagnetic iron oxide nanoparticles, we will identify two groups A)patients who underwent neoadjuvant therapy prior to undergoing these MRI scans and B)patients who did not receive neoadjuvant therapy. Quantitative T2* measurements of aortic wall and atherosclerotic plaques will be performed and compared in each group.
CaNCURE provides trainees with a 6-month hands-on research experience and one-on-one mentoring by leading researchers in cancer nanomedicine. Projects performed by current and past participants include:
While on co-op, trainees document their research in an e-portfolio. This gives trainees the opportunity to provide regular updates on their research progress, reflect on training they are receiving, and explain how their research fits within the field of cancer nanomedicine. These research e-portfolios can be accessed through individual trainee profiles. The complete collection may be found here.
Presentation at CaNCURE Nanomedicine Day
At the completion of their co-op, trainees are provided with the opportunity to present their research to a wider audience. In our 1st annual CaNCURE Nanomedicine Day, trainees prepared interactive, digital posters to display on electronic poster boards. Over 100 faculty, students, and researchers attended our first event!
Check out the news article and congrats to all the poster winners!
Jordan Harris: Most Innovative Cancer Research Award
Jeremy Thong: Best Undergraduate Research Poster Award
Craig Pille: Most Promising Translational Research Award
Bryan Kynnap: Most Promising Basic Science Award
Jordan Harris: Top Chemical Engineering Poster Award