Ferumoxytol is an iron-based super-paramagnetic nanoparticle that is detectable by MRI. It has been previously clinically approved as a drug treatment for anemia in adult patients with chronic kidney disease. Ferumoxytol's magnetic properties and relative safety has led it to be introduced into imaging techniques to track disease progression. A study showed it to effectively show pancreatic inflammation in patient with type 1 diabetes, leading researchers to describe a new, non-invasive method of tracking the progression of the disease. Ferumoxytol has also now been shown to be an effective contrast agent in MR imaging for tumor delineation after neoadjuvant (pre-operative) therapy in patients afflicted with primary pancreatic adenocarcinoma. The administration of ferumoxytol prior to scanning provides more distinct margins in patients scheduled to undergo a Whipple's procedure. Further research is now being done to exam ferumoxytol's effectiveness in tumor delineation on T1-vibe MRI sequences. It is envisioned that this research will drastically improve the ability of radiologists to image tumors and provide more specific and exact delineations for the surgical removal of pancreatic carcinomas.
CaNCURE provides trainees with a 6-month hands-on research experience and one-on-one mentoring by leading researchers in cancer nanomedicine. Projects performed by current and past participants include:
While on co-op, trainees document their research in an e-portfolio. This gives trainees the opportunity to provide regular updates on their research progress, reflect on training they are receiving, and explain how their research fits within the field of cancer nanomedicine. These research e-portfolios can be accessed through individual trainee profiles. The complete collection may be found here.
Presentation at CaNCURE Nanomedicine Day
At the completion of their co-op, trainees are provided with the opportunity to present their research to a wider audience. In our 1st annual CaNCURE Nanomedicine Day, trainees prepared interactive, digital posters to display on electronic poster boards. Over 100 faculty, students, and researchers attended our first event!
Check out the news article and congrats to all the poster winners!
Jordan Harris: Most Innovative Cancer Research Award
Jeremy Thong: Best Undergraduate Research Poster Award
Craig Pille: Most Promising Translational Research Award
Bryan Kynnap: Most Promising Basic Science Award
Jordan Harris: Top Chemical Engineering Poster Award