A Comprehensive Approach to Cancer Treatment Using Magnetic Nanoparticles: From Basic Engineering to In Vivo Studies

The use of magnetic nanoparticles for biomedical applications, in particular cancer treatment, has been investigated for more than a decade. In vivo temporal and spatial control are still challenges that must be faced in order to make the clinical application of these systems a reality.  Our work has focused on the in depth understanding of the nanoparticle’s surface properties on the in vitro and in vivo behavior of colloidally stable particles.  This presentation will summarize lessons learned and the contributions of our work in this area.

Dr. Madeline Torres-Lugo is a Professor in the Department of Chemical Engineering at the University of Puerto Rico, Mayaguez Campus. She has extensively worked on the medical application of biomaterials, design and characterization of drug delivery devices, as well as their interactions with tissues. Currently, her research focuses on various areas including: (i) design and characterization of novel nanoscale and microscale drug delivery systems for poorly absorbed drugs, (ii) investigation of the mechanisms of interaction between carrier/drug, carrier/tissue, and (iii) understanding in vitro and in vivo transport mechanisms. The researcher expertise also includes ample knowledge of free radical polymerization, dispersion polymerization, Fourier transform infrared spectroscopy, confocal laser scanning microscopy, and human cell culture.