Silicon particle delivery to tumors using biomimicry, active, and passive accumulation mechanisms

Our ability to treat tumors using nanoparticles is highly dependent on how successfully we can overcome biophysical barriers in the body.  Come learn about how we can engineer multistage particles to perform unique functions in body, such as accumulate in tumors without using the EPR effect, overcome acquired drug resistance, and selectively migrate across inflamed endothelium.

 

AnneAnne L van de Ven is an Associate Research Scientist at Northeastern University, where she combines high throughput nanoparticle synthesis with quantitative imaging and multiscale modeling to study and optimize cancer treatment in preclinical animal models. As Assistant Director of CaNCURE program and the newly funded Nanomedicine Academy, she is highly involved in the education and training of future of nanomedicine leaders. Anne received her Ph.D. in Bioengineering from Rice University in 2008. From 2009 to 2013, she developed optical techniques for real-time monitoring nanoparticle-based drug delivery and treatment response under the supervision of Dr. Mauro Ferrari. Dr. van de Ven has 12+ years experience in translational nanomedicine, clinical collaboration, and pre-clinical experimental design. Her areas of expertise include: intravital microscopy, optical instrumentation, nanoparticle design and characterization, drug delivery, and animal models of cancer.