Simple Applications of Nanomaterials in Point-of-Care Diagnostics

The idea of nanomaterials invokes a picture of cutting edge technologies and massive costs. In reality, nanomaterials can be quite simple and inexpensive to produce and can enable some of the most critically important applications in healthcare.  In this seminar, we will discuss a particularly significant nanomaterial — the gold nanoparticle — and its role in developing point-of-care diagnostic assays.

The Mace group applies a multidisciplinary approach—combining aspects of chemistry, materials science, biophysics, and engineering—to study the properties of interfaces, develop new materials, and solve outstanding problems in global health. Immiscible Systems.  When mixed, many solutions of polymers, surfactants, and salts form immiscible phases.  We are interested in characterizing the properties of the interfaces between immiscible liquid phases and applying immiscible systems to the study of complex mixtures.  We are particularly interested in those immiscible systems that share water as a common solvent.  Paper Diagnostics. Successful implementation of point-of-care diagnostics has the potential to affect the global management of diseases. Paper is an attractive platform with which to develop assays designed specifically for the developing world because the infrastructure required to develop them is minimal and the materials needed to manufacture them are inexpensive.  We will develop new materials that can enable biochemical assays that are not currently possible using paper alone.