Wirelessly Controlled Implants to Deliver Medicines and Sense Biological Signals
This presentation will discuss the development of a microchip-based implant is a self-contained, hermetically-sealed, drug delivery device that is easy to implant and remove in a physician’s office setting. The implant has the ability to store 100’s of therapeutic doses of a drug over months and years, and release each dose at precise times. The device can be controlled by the patient and/or clinician via a wireless remote or can be programmed to release drug on a pre-determined schedule. The implant has been clinically-validated in human studies delivering PTH in osteoporosis patients and the most advanced version of the system is fully programmable via wireless communications to adjust dosing by the physician and/or patient. The basics of the device design and functionality for use in drug delivery and sensing applications will be discussed along with its potential to be developed to replicate the function of an artificial gland.
Dr. Cheryl R. Blanchard is CEO of Microchips Biotech, Inc., a company developing implantable drug delivery devices designed to provide daily drug dosing for periods of up to many years of therapy. Prior to that, she was the Senior Vice President and Chief Scientific Officer at Zimmer, Inc. an orthopedic implant manufacturer. In that role she was responsible for Research and Development, Quality, Regulatory and Clinical Affairs, and Health Economics. She was also a member of Zimmer’s executive committee and built and served as general manager of the Zimmer Biologics business. Previous to Zimmer, Blanchard built and led the medical device practice at Southwest Research Institute while also serving as an adjunct professor at the University of Texas Health Science Center, both in San Antonio, TX. She holds a B.S in Ceramic Engineering from Alfred University and an M.S. and Ph.D. in Materials Science and Engineering from the University of Texas at Austin. She is also a member of the National Academy of Engineering.