Progress Towards Rational Cancer Therapy

Friday, November 10, 2017 3:25 PM

posted in: Joint IGERT Nanomedicine and CaNCURE Seminar

Dr. Zdravka Medarova Associate Professor in Radiology, Harvard Medical School   Progress Towards Rational Cancer Therapy Over 90% of deaths from cancer are, in fact, due to metastasis and not the primary tumor. However, development of cancer therapeutics is traditionally focused on the primary tumor, which is partly the reason behind the poor outcomes in […]

Nanomedicine in Cancer

Friday, November 3, 2017 3:25 PM

posted in: Joint IGERT Nanomedicine and CaNCURE Seminar

Karen Liby, Ph.D. Associate Professor at Pharmacology & Toxicology, Michigan State University   Despite tremendous progress in our understanding of the biology of cancer, the translation of these advances into a clinical benefit has not kept pace, as the number of deaths from cancer remain unacceptably high. However, rapid advancements in nanomedicine provide opportunities to […]

Biomedical Applications of Magnetic Nanoparticles: Remote Control of Cells

Friday, October 27, 2017 3:25 PM

posted in: Joint IGERT Nanomedicine and CaNCURE Seminar

Jon Dobson, Ph.D. J. Crayton Pruitt Family Department of Biomedical Engineering & Department of Materials Science and Engineering, University of Florida The use of magnetic micro‐ and nanoparticles for biomedical applications was first proposed in the 1920s as a way to measure the rheological properties of the cytoplasm. Since that time, particle synthesis techniques and […]

In Vivo Imaging Guides Prediction and Optimization of Nanomedicine Action in Cancer

Friday, October 20, 2017 3:25 PM

posted in: Joint IGERT Nanomedicine and CaNCURE Seminar

Dr. Miles Miller Assistant Professor of Radiology, MGH Drug-loaded therapeutic nanoparticles have been developed to deliver drugs more safely and effectively to tumors.  In principle, the “enhanced permeability and retention” (EPR) effect operates to improve selective tumoral nanomedicine delivery via features including hyper-permeable tumor vasculature and dysfunctional lymphatics; however, in practice, EPR effects are often […]

Blood trails: nanotechnology-enabled biomarker quantification for early disease detection

Friday, October 13, 2017 3:25 PM

posted in: Joint IGERT Nanomedicine and CaNCURE Seminar

Dr. Tony Hu’s research focuses on developing and validating integrated nanotechnique-based strategies for marker discovery and molecular diagnostics in peripheral blood samples to provide a translatable solution for personalized medicine. His innovations aim to fill current gaps in early detection, real-time therapy monitoring and effective prognostics. Instead of competing on lowering the detection limit of […]