CaNCURE Mentors


Jin-Rong Zhou, Ph.D.


Associate Professor of Surgery
Harvard Medical School




jrzhou@bidmc.harvard.edu

Biography: I received a Ph.D. degree in Nutritional Sciences at University of Illinois, Urbana-Champaign in 1994. After a postdoctoral training in bionutrition and cancer prevention at Beth Israel Deaconess Medical Center/Harvard Medical School and a National Research Service Award from the National Institutes of Health, I was appointed as an Instructor, an Assistant Professor, and an Associate Professor in Department of Surgery, Harvard Medical School. I have been the Director of Nutrition/Metabolism Laboratory at Department of Surgery, Beth Israel Deaconess Medical Center since 1998. My research has been widely supported by several funding organizations, such as the National Institutes of Health (NIH), Department of Defense, Susan Komen Breast Cancer Foundation, American Institute for Cancer Research, Massachusetts Department of Public Health, Cancer Research and Prevention Foundation and Nichimo Company in Japan. I have published over 60 peer-reviewed original research papers, review papers and book chapters/editorials. I have been the member/ad hoc member in over 30 study sections and special emphasis panels for the NIH, and have also served several review panels for other national and international organizations. I have been the ad hoc reviewer for about 60 scientific journals, the Editorial Board members for several scientific journals, and the Editors-in-Chief for the Nutrition and Metabolic Insights and the Journal of Health Science.

Research and Expertise: The focus of my research is the study of the role that diet and nutrition may play in the prevention and treatment of certain types of cancer such as breast, prostate, pancreatic and bladder cancers, and to investigate the mechanisms of action of active dietary and nutritional components. My important research strategies include application of an integrated research system to evaluate the efficacies of dietary/nutritional regimens, to elucidate underlying cellular, molecular and epigenetic mechanisms of actions, to identify novel anti-cancer components, and to define risk factors of cancer development and progression for designing effective nutritional regimens for cancer prevention. By using in vitro and clinically relevant animal models, we are identifying effective dietary/nutritional regimens for cancer prevention. We are applying cell function-guided extraction, fractionation and purification strategies to identify active components from Chinese herbal medicines for the prevention and therapy of cancer. In addition, we are investigating the roles that nutritional and natural components may play in targeting cancer stem cells. Our research findings can be directly translated into future clinical investigations.

Website

Publications


Featured Publications

NanomedicinePhD

nanophores

SiRNA nanocomplexes