Research – CaNCURE

Genomic sequencing of translocations in multiple myeloma patients of differing stages

Rashmika Beesam with Dr. Irene Ghobrial (DFCI)

Sustained-release talazoparib for treatment of BRCA1-deficient ovarian cancer

Daniela Portela with Dr. Srinivas Sridhar (NU)

Understanding and overcoming resistance to PARP inhibitors in ovarian cancer patients

Michelle Wang with Dr. Cesar Martin Castro (MGH)

Rapid hormone receptor classification using molecular profiling & imaging of breast cancer

Marina DiPiazza with Dr. Nathalie Agar (BWH)

MRI imaging of human vascular dysfunction using ferumoxytol nanoparticles

Zachary Chao with Dr. Srinivas Sridhar (NU)

Molecular imaging for detection of gastrointestinal & pancreatic cancers

Shriya Krishna with Dr. Zdravka Medarova (MGH)

Resistance to immunogenic cell death in the treatment multiple myeloma with bortezomib

Delaney Vinaixa with Dr. Kenneth C. Anderson (DFCI)

Gadolinium-based nanoparticles for lung cancer radiation dosage enhancement

Ifeanyi Mbanugo with Dr. Ross Berbeco (DFCI)

Genetic differences between early-onset and late-onset colorectal cancer patients

Arika Dwivedi with Dr. William Hahn (DFCI)

Improving anti-VEGF treatments through exercise training

Sarah Shiferaw with Dr. Dai Fukumura (MGH)

Nanoformulated PARP inhibitors for treatment of ovarian & breast cancers

Merline Senat with Dr. Srinivas Sridhar (NU)

Paclitaxel polymer films to prevent local recurrence of sarcoma in murine models

Katalina Baehring with Dr. Yolonda Colson (MGH)

Granzyme M-/Gasdermin E-induced pyroptosis conservation in mice

Grant Tucker with Dr. Pasi A. Janne (DFCI)

Role of TP53 in persister cell formation and chemotherapy resistance

Connor Bossi with Dr. Timothy A. Springer (BCH)

Role of RPS15 mutations on chronic lymphocytic leukemia development

Christina Curran with Dr. Catherine Ju-Ying Wu (DFCI)

Evaluation of implantable anti-cancer therapeutics for localized drug delivery

Bryanna Testino with Dr. Daniela M. Dinulescu (BWH)

Focused ultrasound for blood brain barrier disruption and tumor ablation

Ryo Tsuda with Dr. Nathan McDannold (BWH)

miR-710 as a therapeutic target in human metastatic breast cancer

Ellen Smith with Dr. Zdravka Medarova (MGH)

Drug/Metabolite quantification of cancer tissue samples using MALDI-MS

Daniela Ruiz with Dr. Nathalie Y.R. Agar (BWH)

Sustained release of nanoTalazoparib for ovarian cancer treatment

Alexis Robinson with Dr. Sri Sridhar (NU)

Surface-enhanced spatially offset resonance raman spectroscopy for cancer detection

Nicole Riepl with Dr. Atul Shinagare (DFCI)

Nano-smart radiotherapy biomaterials for combining radiotherapy & immunotherapy

Geraud Richards with Dr. Wilfred Ngwa (DFCI)

Defining the t(4,14) mechanism in multiple myeloma progression

Katarina Nilsson with Dr. Irene Ghobrial (DFCI)

Lymphatic drainage and immunosurveillance of brain tumors

Alexandra Melloni @ BWH with Dr. Khalid Shah

Extracellular vesicle characterization for early detection of paclitaxel resistance in triple negative breast cancer

Charlotte McLean with Dr. Cesar Martin Castro (MGH)

Tumor treatment by intra- or peri-tumoral injection of [177Lu]-Feraheme nanoparticles

Sarah Johnson with Dr. Georges El Fakhri (MGH)

Combining radiolabeled drugs & PET to study cancer cell-mediated immune response

AAlyssa Granito with Dr. Umar Mahmood (MGH)

Flavonoid-loaded ACE2 nanodrones to target lung cancer cells

Amanda Fam with Dr. G. Mike Makrigiorgos (DFCI)

Ferumoxytol for non-invasive magnetic resonance imaging of neoplastic microvasculature

Benjamin Dottinger with Dr. Srinivas Sridhar (NU)

Development & evaluation of a theranostic probe for image-guided treatment of oral cancer

Leslie Contreras with Dr. Tayyaba Hasan (MGH)

Leveraging the synergistic anti-proliferative effect of SHMT2 and CDK4 in triple negative breast cancer

Brian Shim with Dr. William Hahn (DFCI)

Silica-based bismuth gadolinium nanoparticles for radiation dose enhancement in lung cancer

Meghna Iyer with Dr. Ross Berbeco (DFCI)

Cancer Nanomedicine Research