CaNCURE is a partnership between Northeastern University and
Dana-Farber / Harvard Cancer Center funded by the National Cancer Institute.
“During my previous co-op, I worked with many patients who either had cancer or had side effects from radiation treatments 10-15 years later. Watching this process made me wonder about alternative treatment methods that would cause fewer harmful side-effects. As someone aiming to enter the field of medicine, participating in CaNCURE and exploring the possibilities behind nanomedicine allows me to see how cancer treatment is continuing to develop.”
Bioengineering, '22
Multiplexed cellular fluorescent imaging in head and neck squamous cell carcinomas (HNSCC) for different markers to predict patient specific response rates to immunotherapy and for mapping of the tumor microenvironment (TME).
Molecular Biology, '21
Role of ESRP1/ESRP2 splicing regulators in the development of Triple-Negative Breast Cancer
Behavioral Neuroscience, '23
In vivo investigation of the pathogenesis and development of pituitary adenomas in relation to the loss of MEG3 expression
Health Science, '21
The Role of CD8+ and CD4+ in the Tumor Microenvironment (TME) after Controlled Exercise in E0771/M3C Breast Cancer Models
Health Science, '21
The Development and Characterization of Monoclonal Antibodies for Integrins and TGF-b
Biology and Mathematics, '21
Understanding the Role of Epigenetics in Multiple Myeloma Progression
Health Science, '21
Monocyte Subtype Determination by Labeling with Feraheme Nanoparticles
Health Science, '21
Metabolite Quantification from Cancer Tissues using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging
Business (w Concentration in Healthcare Management and Consulting), '23
Nano-Talazoparib and Nano-Dinaciclib Combination Therapy for Lung Cancer Cells
Health Science, '21
Triple-targeted Photonanomedicine: A Strategy to Treat Heterogeneous Tumors
Cell and Molecular Biology, '21
Using smart biomaterials with immunoadjuvants to treat metastatic breast cancer
Chemical Engineering, '21
Enhanced delivery of camptothecin and doxorubicin conjugates with hyaluronic acid for the treatment of Glioblastoma using microbubble-mediated focused ultrasound
Health Science, '22
Integrated diffraction-based diagnostic for point-of-care screening
Biology, '21
Impact of RPS15 mutation on development and progression of chronic lymphocytic leukemia
Health Science, '20
RHAMM splicing in multiple myeloma (MM) and its implications for immunotherapy
Health Sciences, '20
Expression of anti-apoptotic proteins in pancreatic cancers: A potential barrier to photodynamic killing
Health Sciences, '20
Synthesis of DFO-Lys(PEG30k)-Cys(Cy3) to examine macropinocytosis in human and mouse cancers in vitro
Health Sciences, '20
Targeted Delivery of Talazoparib to Treat Non-Small Cell Lung Cancer
Health Sciences, '20
Detection of low-level mutations in DNA obtained from cancer patients, using PCR and nano-PCR
Behavioral Neuroscience, '20
Assessment of atherosclerotic changes following neoadjuvant therapy using ferumoxytol as contrast imaging agent
Chemical Engineering and Biochemistry, '21
Codelivery of tumor suppressor mRNA and anti-cancer drug in cancer treatment
Biochemistry, '20
Assessing sufficiency of the Tip60/p400 complex in inducing transcription of Merkel Cell Polyomavirus Small T antigen target genes.
Biochemistry, '21
Targeted Delivery of Liposomes using PARP Inhibitors to Treat Non-Small Cell Lung Cancer
Health Sciences, '21
Analyzing metastasis through targeted miRNA nanotherapy in aggressive breast cancer
Cell and Molecular Biology, '21
The Nano-plasmonic Exosome (nPLEX) Assay for Pancreatic Ductal Adenocarcinoma Diagnosis and Prognosis
Behavioral Neuroscience, '19
Characterization of Nano-Dinaciclib in Combination with Nano-Talazoparib for the Treatment of Breast Cancer
Chemical Eng / Biochemistry, '21
Creating Animal Models of High-grade Serous Ovarian Cancer Cells
Health Science, '19
Molecular Analysis of Plasma Vesicles for Early Pancreatic Cancer Detection
Health Sciences, '19
Characterization of Targeted PARP-inhibitor Nanoformulations In Vitro and In Vivo
Health Sciences, '19
Investigation of a miRNA associated with cancer metastasis. Proj 2-Development of a novel nanoparticle for MPI analysis of thromboses
Cell and Molecular Biology, '21
Use of CT Texture Analysis for Characterization and Prognostication of Incidental Adnexal Lesions
Health Science, '19
Development of Smart INCeRT Brachytherapy Spacers via PLGA and Docetaxel for Combined Chemo-Radiation Therapies in Prostate Cancer
Health Science, '19
PDT and PIT with Chemotherapy for Treatment of 3D Ovarian Cancer Nodules Under Flow and Static Conditions
Health Science, '19
Evaluation of deep learning approaches in an integrated PET/MRI scanner to generate pelvis attenuation maps and characterize prostate cancer
Biochemistry, '20
Discovering the Genetic Mechanism of Enhanced Metastatic Colonization in SMAD4 Mutant Tumors
Health Sciences, '19
Investigating the use of Feraheme to monitor the immune response by PET in general inflammation and specific immune cell populations
Health Science, '18
Delivery of Titanium Dioxide Nanoparticles via Biodegradable PLGA Dissolving Microneedles for Sustainable Release
Bioengineering, '19
Development of a Point of Care Assay for Detecting High Risk HPV in Resource Limited Settings
Biology, '19
Analysis of DREAM and E2F1 Competition for Cell Cycle Promoters during G1.
Mechanical Engineering, '20
Assessment of Atherosclerotic Changes using Ferumoxytol as MRI Contrast Agent
Chemical Engineering, '19
In vivo imaging of targeted drug delivery to HER2 positive cancer cells
Health Science, '18
Online monitoring and image-guided treatment of chemoresistant micrometastases
Health Science, '18
Co-delivery of protective substrate and chemotherapy drugs via lipid Bilayer Mesoporous Silica Nanoparticles
Health Science, '18
miRNA analysis in mouse model of metastatic breast cancer. (Proj 2) The inhibition of PD-L1 on a Pan02 cell line w/ siRNA-nanodrug & gemcitabine treatment
Health Science, '18
The Assessment and Comparison of Ferumoxtran as Contrast Imaging Agent in Patients with Pancreatic Cancers.
Biochemistry, '19
Development of PSMA-targeting nanoparticles for positron emitting tomography imaging in prostate cancer using animal models
Health Science, '18
Use of a Triblock Copolymer Hydrogel for Controlled Release of Cisplatin and BMN-673
Biology, '18
Radiotherapeutic synergism of thermogelling cisplatin-loaded polymers for cervical cancer treatment
Cell and Molecular Bio, '18
Development of a novel nanogel for non-invasive transdermal delivery of cancer vaccines using hyaluronic acid
Chemical Engineering, '18
Nanoencapsulation of tyrosine kinase inhibitors and their effects on pathway inhibition
Biology/Math, '17
Biological mechanisms of gold nanoparticle-enhanced radiation therapy of prostate cancer
Biology, '19
Assessment of neoadjuvant therapy-induced atherosclerotic changes using ferumoxytol-enhanced MR imaging
Health Sciences, '17
Uptake and localization of nanoparticles in prostate and lung cancer cells as a function of time and nanoparticle type
Biomedicial Physics, '17
Implementation of novel MR-based attenuation correction in PET/MR pelvic scans
Behavioral Neurosci, '19
Assessing the reproducibility of MRI-based brain tumor measurements between both observers and MRI vendors
Health Science, '17
Combined delivery of targeted liposomal chemotherapeutics and photodynamic therapy to treat pancreatic cancer
Health Sciences, '17
Optimizing murine cells for in vitro modeling of high-grade serous ovarian cancer
Health Sciences, '18
Protein-encapsulated nanoparticles for oral delivery of anti-mitotic agents in prostate cancer
Biochemistry, '18
Injectable thermogelling cisplatin-loaded hydrogels for combined chemo-radiation therapy in cervical cancer
Health Sciences, '17
Investigating the use of iron chelator deferoxamine (DFO)-bearing PEG-like nanoprobes as a multifunctional agent for cancer therapy and PET imaging
Chemical Engineering, '16
Optimization of macrophage-targeted nanoparticles for positron emission tomography imaging in cancer
Biochemistry, '18
Identification of novel therapeutic targets of the Notch1 signaling pathway
Behavioral Neurosci, '17
Radiation enhancement in cancer cells using gold and gadolinium nanoparticles
Behavioral Neurosci, '17
Localized chemo- and chemo-radiation for the treatment of prostate cancer
Biology/English, '17
Tracking pancreatic adenocarcinoma response to treatment using targeted, multi-modal nanoparticles
Physics, '17
Longitudinal assessment of tumor heterogeneity during immunotherapy for metastatic melanoma
Biology, '16
Software with built-in neuroanatomy atlas provides insight into cancer treatment
Health Sciences, '16
Identifying genomic and compound dependencies in undifferentiated sarcomas
Biology, '16
Erythropoietin improves antitumor immune response through reversal of the hypoxic tumor microenvironment
Biochemistry, '16
Capture of circulating tumor DNA through the use of biotinylated poly-lysine affixed to gold nanoparticles
Behavioral Neurosci., '16
Clinical immunotherapy application in metastatic glioblastoma
Health Sciences, '16
Targeting CXCR4/SDF-1a using phytochemicals to inhibit progression and metastasis of pancreatic cancer
Health Sciences, '16
Mechanistic and modeling studies of lipid nanoemulsions impact on oral lapatinib absorption
Chemical Engineering, '17
Surface-targeting, ligand-switching nanoparticles for mitochondrial drug delivery in prostate cancer
Health Sciences, '16
Iron-chelating PEG-like nanoprobes as therapeutic and 89Zr/PET imaging agents
Health Sciences, '16
MCT1 Transporter Inhibition of IMR90 Cells Expressing Inducible Merkel Cell Carcinoma Small T Antigen